Endocrine Abstracts

The risk of malignancy in thyroid nodules correlates with the presence of ultrasound features. In adults, ultrasound risk-classification systems have been proposed to indicate the need for further invasive diagnosis. Furthermore, elastography has been shown to support differential diagnosis of thyroid nodules. The purpose of our study was to assess the application of the American Thyroid Association (ATA) and British Thyroid Association (BTA) ultrasound risk-classification sys...

Introduction: Ultrasonography-guided fine-needle aspiration biopsy (ug-FNAB) is recommended as the first and most important step in the management of nodular thyroid disease.Material and methods: We compared the results of ultrasonography examination (US) and the ug-FNAB of the thyroid gland with postoperative histpathological findings in 387 patients with thyroidectomy operated on (61 cytological and 326 clinical indication).Resul...

A higher incidence of nodular goitre and less differentiated types of thyroid carcinoma have been observed in iodine deficient regions. North-Eastern Poland was an area with a moderate deficiency of iodine until the introduction of the mandatory salt iodination in 1997 (30±10 mg KJ/kg NaCl). The aim of our study was to compare the incidence of goitre, thyroid carcinoma and urine excretion of iodine in the inhabitants of the North-Eastern Region of Poland in 1997 and 2005....

Aim: In Hashimoto thyroiditis (HT) thyroid cells show abnormalities in the intracellular iodine metabolism, associated with the changes in the expression of key proteins involved in the biosynthesis of: thyroid peroxidase (TPO), thyroglobulin (Tg), sodium iodide symporter (NIS) and pendrin. The aim of the present study was to compare the expression of thyroid-specific genes, such as NIS and Tg, as well as pro-inflammatory cytokines, such as tumor necrosis factor-α (TNF&#9...

Before the introduction of mandatory salt iodination in 1997 the North-Eastern Region of Poland was known to be a moderate iodine deficiency area. Moreover, it was one of the mostly contaminated regions after the Chernobyl accident in 1986. The aim of our study was to evaluate the descriptive epidemiological features of incident thyroid cancers diagnosed among the residents of this area between 1996 and 2005. The Regional Cancer Surveillance Program was used to collect data on...

Background: The excessive secretion of parathormone by parathyroid glands is a common disorder known as hyperparathyroidism. With a prevalence of 0.1-0.4 percent in the general population and 2-4 percent in post-menopausal women, primary hyperparathyroidism is the third most frequently reported endocrine disorder. According to estimates, the prevalence of primary hyperparathyroidism has escalated in recent years, probably due to the increasing rate of parathormone and calcium ...